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Molecular Karyotyping

With the advent of “Oligonucleotide arrays", Molecular Karyotyping done by metaphase chromosomes have been replaced by these arrays to provide a higher resolution as fine as just a few Kilobases (Kb).

  • Affymetrix´ and Agilent´s microarray platforms are among the world’s leading DNA chip technologies.
  • Agilent’s CGH arrays provide a powerful tool for the genome-wide detection of CNVs.
  • Affymetrix´ Human SNP Array 6.0 can be used for SNP Genotyping and for the detection of genetic imbalances, such as CNVs, loss-of-heterozygosity, and copy number-neutral LOH (uniparental disomy).