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Gene Regulation

BioXplore is proud in offering and tailoring most types of
transcriptomics services to meet your research objectives. 

Total RNA-Seq with Ribosomal Reduction

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BioXplore’s comprehensive services to analyze mRNA and long non-coding RNA using sequencing with Illumina platforms. Total RNA-Seq with ribosomal reduction selectively removes ribosomal RNA from total RNA samples. Whole transcriptome sequencingis the ideal approach to gain comprehensive genome-wide view of the transcriptome, map genes by untranslated region (UTR) and by characterizing exon boundaries. Total RNA-Seq provides to analyse splicing and alternative splicing mechanisms and to investigate transcriptomes of human and non-human origin.

Small RNA Sequencing

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BioXplore delivers complete services for characterization and measurement of the levels of a wide variety of small RNA classes. Small RNA sequencing is an RNA-Seq approach that targets small RNAs as input material. These noncoding small RNAs include important regulatory elements like miRNA, siRNA and piRNA. Small/mi RNA analysis provides the ability to discover, measure and compare expression of know microRNAs and other small non-coding RNA. It also allows to detect novel microRNA targets.

mRNA Sequencing

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BioXplore has been providing the accurate and affordable RNA-Seq. mRNA-Seq can provide valuable information about splicing patterns, splicing variants, gene isoforms, single nucleotide polymorphisms and post transcriptional modifications

Dual RNA-seq

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Dual RNA-seq has been shown to monitor all classes of coding and noncoding transcripts of both host and pathogen simultaneously. BioXplore offers high-resolution, affordable dual RNA-seq service to understand the molecular mechanisms of interactions between hosts –pathogens.

ISO-SEQ on PacBio Sequel

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Single Molecule, Real-Time (SMRT) Sequencing and Iso-Seq analysis allows you to cover complete transcript from the 5' end to the 3'-poly A tail without the need of fragmentation to obtain full-length cDNA sequences. Iso-Seq is useful to identify new transcripts and new introns, thus accurately identifying isoforms, alternative splicing sites, fusion gene expression, and allelic expression.